When Scripture bids us leave off self-concern, it not only erases from our minds the yearning to possess the desire for power, and the favor of men, but it also uproots ambition and all craving for human glory and other more secret plagues. Accordingly, the Christian must surely be so disposed and minded that he feels within himself it is with God he has to deal throughout his life. In this way, as he will refer all he has to God’s decision and judgement, so will he refer his whole intention of mind scrupulously to Him. For he who has learned to look to God in all things that he must do, at the same time avoids all vain thoughts. This, then, is that denial of self which Christ enjoins with such great earnestness upon his disciples at the outset of their service. When it has once taken possession of their hearts, it leaves no place at all first either to pride, or arrogance, or ostentation; then either to avarice, or desire, of lasciviousness, or effeminancy, or to other evils that our self-love spawns.

Then Jesus told his disciples, “If anyone would come after me, let him deny himself and take up his cross and follow me. -Matthew 16:24

For people will be lovers of self, lovers of money, proud, arrogant, abusive, disobedient
to their parents, ungrateful, unholy, heartless, unappeasable, slanderous, without self-control, brutal, not loving good, treacherous, reckless, swollen with conceit, lovers
of pleasure rather than lovers of God, having the appearance of godliness, but denying
its power. Avoid such people. -2 Timothy 3:2-5